Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243239 | 1.00 | CA12 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1051273 | 0.94 | ALDH1A1 (0.52) | CA1CA2PARP10PARP3ALDH1A1 | |
| SCHEMBL30053335 | 0.91 | PARP10 (0.50) | CA1CA2PARP10PARP3ALDH1A1 | |
| Trimethylammonium SCHEMBL461393 | 0.86 | PARP10 (0.46) | CA1CA2PARP10PARP3ALDH1A1 | |
| Terephthalamide SCHEMBL28201048 | 0.83 | TSHR (0.60) | CA1CA2MKNK1MKNK2PARP10 | |
| SCHEMBL15764248 | 0.82 | ERN1 (0.55) | ERN1HDAC2PARP1 | |
| SCHEMBL1002578 | 0.82 | CA2 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10245562 | 0.81 | ALDH1A1 (0.56) | CA12CA1CA2CA9CA14 | |
| SCHEMBL19048679 | 0.81 | PARP10 (0.69) | CA12CA1CA2CA9CA14 | |
| SCHEMBL1676005 | 0.81 | ALDH1A1 (0.56) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018868-A1 | SUBSTITUTED 2-HYDROXY-4-(2-(PHENYLSULFONAMIDO)ACETAMIDO)BENZOIC ACID ANALOGS AS INHIBITORS OF STAT PROTEINS | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-02-09 | — | — | WO | disclosed |