Terephthalamide

Terephthalamide

SCHEMBL28201048

C=Cc1ccccc1.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C19 P33261 2/20 0.60
PARP1 P09874 2/20 0.60
POLB P06746 1/20 0.60
MAPT P10636 1/20 0.60
RECQL P46063 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
HSD17B10 Q99714 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
ALDH1A1 P00352 2/20 0.58
PARP10 Q53GL7 8/20 0.52
PLA2G10 O15496 1/20 0.52
PLA2G2A P14555 1/20 0.52
MKNK1 Q9BUB5 1/20 0.44
MKNK2 Q9HBH9 1/20 0.44
PARP15 Q460N3 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL8459253 0.96 MAPT (0.67) TSHRCYP3A4CYP2C19PARP1POLB
SCHEMBL1051273 0.89 ALDH1A1 (0.52) TSHRCYP3A4CYP2C19PARP1POLB
SCHEMBL30053335 0.87 PARP10 (0.50) TSHRCYP3A4CYP2C19PARP1POLB
Styrene SCHEMBL5164588 0.87 ALDH1A1 (0.70) TSHRCYP3A4CYP2C19PARP1POLB
Styrene SCHEMBL2033347 0.87 ALDH1A1 (0.70) TSHRCYP3A4CYP2C19PARP1POLB
Styrene SCHEMBL27925811 0.85 ALDH1A1 (0.67) TSHRCYP3A4CYP2C19PARP1POLB
Styrene SCHEMBL27496207 0.85 ALDH1A1 (0.67) TSHRCYP3A4CYP2C19PARP1POLB
Anthraquinone SCHEMBL28095794 0.83 L3MBTL1 (0.45) TSHRCYP3A4CYP2C19PARP1POLB
SCHEMBL10243239 0.83 CA12 (0.50) TSHRCYP3A4CYP2C19PARP1POLB
SCHEMBL10247611 0.83 CA12 (0.50) TSHRCYP3A4CYP2C19PARP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107735001-A Wrap up reception system and method 蒋帅 2018-02-23 CN disclosed