Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.44 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3286145 | 0.91 | ADK (0.50) | ADKMETTL3METTL14 | |
| SCHEMBL18571878 | 0.86 | ADK (0.58) | ADKMETTL3 | |
| SCHEMBL15381050 | 0.83 | ADK (0.46) | ADKMETTL3METTL14 | |
| SCHEMBL13005628 | 0.81 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL10131093 | 0.81 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL1797344 | 0.81 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL10160817 | 0.81 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL3287852 | 0.81 | ALDH1A1 (0.54) | — | |
| SCHEMBL23544706 | 0.81 | ADK (0.53) | ADKMETTL3METTL14 | |
| SCHEMBL18636459 | 0.81 | ADK (0.53) | ADKMETTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580762-B2 | Substituted purine and 7-deazapurine compounds | Epizyme, Inc. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | Epizyme, Inc. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142625-A1 | Substituted Purine And 7-Deazapurine Compounds | TPMT, DIMT1, DAZAP1 | ADK 221/4885METTL3 64/4885METTL14 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.