Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 3/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.52 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636459 | 0.91 | ADK (0.53) | ADKMETTL3METTL14 | |
| SCHEMBL10160817 | 0.89 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL1797344 | 0.89 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL13005628 | 0.89 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL10131093 | 0.89 | ADK (0.64) | ADKMETTL3METTL14 | |
| SCHEMBL14440901 | 0.88 | ADK (0.63) | ADKMETTL3METTL14 | |
| SCHEMBL14440630 | 0.88 | ADK (0.63) | ADKMETTL3METTL14 | |
| SCHEMBL1689454 | 0.84 | METTL3 (0.55) | ADKMETTL3 | |
| SCHEMBL10060036 | 0.84 | METTL3 (0.55) | ADKMETTL3 | |
| SCHEMBL10079496 | 0.84 | METTL3 (0.55) | ADKMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126999-A1 | USE OF BIOMARKERS IN IDENTIFYING PATIENTS THAT WILL BE RESPONSIVE TO TREATMENT WITH A PRMT5 INHIBITOR | MERCK SHARP & DOHME CORP. (US) | 2021-06-24 | — | — | WO | disclosed |