SCHEMBL10249525

SCHEMBL10249525

Cc1ccc(C[Si](C)(O[Si](C)(Cc2ccc(C)cc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
ACHE P22303 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
AGXT P21549 2/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
CYP2C19 P33261 2/20 0.35
HTT P42858 1/20 0.35
HPGD P15428 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14445705 0.93 HTT (0.39) LMNAPOLBSMN1; SMN2TSHRALOX12
SCHEMBL10249522 0.88 SMN1; SMN2 (0.34) LMNAPOLBSMN1; SMN2PPARGPPARA
SCHEMBL988388 0.79 NR1H2 (0.49) LMNAPOLBSMN1; SMN2TSHRALOX12
SCHEMBL16749887 0.77 CNR2 (0.35) LMNAPOLBSMN1; SMN2CYP2C19HPGD
SCHEMBL989099 0.76 LMNA (0.42) LMNAPOLBSMN1; SMN2TSHRALOX12
SCHEMBL14208869 0.75 LMNA (0.41) LMNAPOLBSMN1; SMN2TSHRALOX12
SCHEMBL10249673 0.74 TAAR1 (0.38) PPARGPPARAHPGDMAPTKMT2A
SCHEMBL13213980 0.74 HTT (0.39) LMNAPOLBSMN1; SMN2TSHRALOX12
SCHEMBL17753742 0.74 DRD2 (0.41) LMNASMN1; SMN2CYP2C19KMT2AIDO1
SCHEMBL17753737 0.73 DRD2 (0.40) LMNANPC1RAB9ACYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188887-B2 Polycarbonate copolymer, coating fluid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer IDEMITSU KOSAN CO., LTD. (JP) 2015-11-17 US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed