Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249525 | 0.93 | LMNA (0.38) | HTTCYP2C19PPARGPPARALMNA | |
| SCHEMBL10249522 | 0.81 | SMN1; SMN2 (0.34) | PPARGPPARALMNAKMT2AMEN1 | |
| SCHEMBL13213980 | 0.78 | HTT (0.39) | HTTCYP2C19PPARGPPARALMNA | |
| SCHEMBL988388 | 0.71 | NR1H2 (0.49) | HTTCYP2C19LMNAKMT2ANR1H2 | |
| SCHEMBL14208869 | 0.71 | LMNA (0.41) | HTTCYP2C19LMNAKMT2AMEN1 | |
| SCHEMBL10249673 | 0.70 | TAAR1 (0.38) | PPARGPPARAKMT2AMAPTHPGD | |
| SCHEMBL5388447 | 0.69 | TSHR (0.42) | LMNANR1H2NR1H3TSHRHPGD | |
| SCHEMBL989099 | 0.68 | LMNA (0.42) | HTTCYP2C19LMNAKMT2AMEN1 | |
| SCHEMBL13870133 | 0.67 | ACHE (0.46) | HTTCYP2C19LMNAKMT2AMEN1 | |
| SCHEMBL10249515 | 0.67 | AGXT (0.43) | HTTACHEALDH1A1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238455-B2 | Mixture of alkali soluble resin, quinonediazide compound and alcohol | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2007-07-03 | — | — | US | disclosed |