SCHEMBL10249526

SCHEMBL10249526

Cc1ccccc1C[Si](C)(O[Si](Cc1ccccc1C)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
MAOB P27338 2/20 0.32
CYP2A13 Q16696 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HPGD P15428 2/20 0.31
CTBP2 P56545 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
ADORA2A P29274 1/20 0.31
KMT2A Q03164 1/20 0.31
ELANE P08246 1/20 0.31
P2RX7 Q99572 1/20 0.31
CDK4 P11802 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10249673 0.90 TAAR1 (0.38) TAAR1ADRA2AADRA2BADRA2CCYP11B1
SCHEMBL17263571 0.88 TAAR1 (0.39) TAAR1ADRA2AADRA2BADRA2CCYP11B1
SCHEMBL10249516 0.74
SCHEMBL12762448 0.71 HSPA5 (0.42) TAAR1KDM4E
SCHEMBL10249514 0.71 TAAR1 (0.43) TAAR1ADRA2AADRA2BADRA2CCYP11B1
SCHEMBL17753741 0.69 TAAR1 (0.40) TAAR1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL17753743 0.68 TAAR1 (0.39) TAAR1ADRA2AADRA2BADRA2CALDH1A1
SCHEMBL38651085 0.67 ADRA2A (0.41) TAAR1ADRA2AADRA2BADRA2CCYP11B1
SCHEMBL10249525 0.66 LMNA (0.38) PPARGPPARAHPGDMAPTKMT2A
SCHEMBL13621397 0.64 TP53 (0.36) ALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed