Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605972 | 0.96 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL10249431 | 0.84 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL10249545 | 0.80 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL1605834 | 0.79 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL1605922 | 0.79 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL1384186 | 0.79 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL1605249 | 0.79 | HSD11B1 (0.41) | HSD11B1 | |
| SCHEMBL1606049 | 0.78 | HSD11B1 (0.30) | HSD11B1 | |
| SCHEMBL1606099 | 0.77 | TAS1R3 (0.33) | — | |
| SCHEMBL14344801 | 0.77 | TAS1R3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010256-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010256-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD3B1, HSD17B1 | HSD11B1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.