SCHEMBL10249733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13152598	0.93	CA12 (0.42)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL13152163	0.90	DYRK1A (0.41)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL13152566	0.90	GRIK2 (0.43)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL10249314	0.89	DYRK1A (0.41)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL13152193	0.89	KDM4E (0.39)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL13152170	0.89	MAPT (0.41)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL10251160	0.87	APP (0.50)	DYRK1AALDH1A1CYP3A4KDM4EMAPK1
	SCHEMBL984838	0.87	HTT (0.43)	DYRK1AALDH1A1CYP3A4KDM4EMAPK1
	SCHEMBL13152568	0.87	APP (0.45)	DYRK1AALDH1A1KDM4EMAPK1HTT
	SCHEMBL13152171	0.85	DYRK1A (0.40)	DYRK1AALDH1A1CYP3A4KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.