Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10258235 | 0.86 | CETP (0.44) | KMT2ACYP3A4KDM4EALDH1A1ABCB1 | |
| SCHEMBL10257175 | 0.80 | HTR2C (0.50) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL10251800 | 0.80 | RIPK1 (0.38) | SMN1; SMN2TSHRKMT2AMEN1CYP3A4 | |
| SCHEMBL21310317 | 0.78 | GRM2 (0.40) | RIPK1GRM2 | |
| SCHEMBL10257159 | 0.77 | CCR5 (0.36) | SMN1; SMN2TSHRKMT2AMEN1MAPT | |
| SCHEMBL18175828 | 0.76 | CYP3A4 (0.36) | SMN1; SMN2TSHRKMT2AHPGDCYP3A4 | |
| SCHEMBL1908573 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRKMT2AMEN1NPC1 | |
| SCHEMBL597215 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRKMT2AMEN1NPC1 | |
| SCHEMBL9974772 | 0.76 | CYP3A4 (0.36) | SMN1; SMN2TSHRKMT2AHPGDCYP3A4 | |
| SCHEMBL9929765 | 0.76 | CYP3A4 (0.36) | SMN1; SMN2TSHRKMT2AHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142916-A1 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142916-A1 | PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID | MME, REN, PAH | SMN1; SMN2 1166/4885TSHR 2857/4885KMT2A 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.