Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.78 |
| ▸ | CNR1 | P21554 | 3/20 | 0.78 |
| ▸ | HPGDS | O60760 | 1/20 | 0.71 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.71 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.71 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.71 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.71 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.71 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.71 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.71 |
| ▸ | NAMPT | P43490 | 3/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253402 | 0.94 | CNR2 (0.88) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL10253415 | 0.89 | CNR2 (0.80) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL10253329 | 0.88 | CNR2 (0.79) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL10257721 | 0.88 | CNR2 (1.00) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL4559682 | 0.87 | MAPT (0.73) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL2677762 | 0.86 | CNR2 (0.69) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL14306236 | 0.84 | MAPT (0.69) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL13148217 | 0.84 | ALDH1A1 (0.66) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL14934392 | 0.83 | USP2 (0.68) | CNR2CNR1HPGDSPRKAB2PRKAG1 | |
| SCHEMBL6153200 | 0.82 | KMT2A (0.69) | CNR2CNR1HPGDSNAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173638-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173638-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009964-A1 | Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | CNR2 1/4885CNR1 2/4885HPGDS 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.