Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686640 | 0.83 | LMNA (0.41) | ESR1ESR2TSHRLTA4HL3MBTL1 | |
| SCHEMBL14247704 | 0.82 | ESR1 (0.35) | ESR1ESR2TSHRLTA4HGLA | |
| SCHEMBL1027104 | 0.82 | GAA (0.36) | ESR1ESR2TSHRLTA4HGLA | |
| SCHEMBL1686817 | 0.79 | LTA4H (0.44) | TSHRLTA4HL3MBTL1TP53LMNA | |
| SCHEMBL645564 | 0.78 | LTA4H (0.38) | ESR1ESR2TSHRLTA4HGLA | |
| SCHEMBL1686459 | 0.78 | LTA4H (0.44) | TSHRLTA4HTP53MEN1KMT2A | |
| Methyl Alcohol SCHEMBL27925740 | 0.77 | ESR1 (0.35) | ESR1ESR2TSHRLTA4HGLA | |
| SCHEMBL8853348 | 0.77 | ESR1 (0.36) | ESR1ESR2TSHRLTA4HGLA | |
| SCHEMBL1686800 | 0.77 | ALDH1A1 (0.40) | ESR1ESR2TSHRMEN1KMT2A | |
| SCHEMBL18043734 | 0.77 | TSHR (0.35) | ESR1ESR2TSHRLTA4HGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962091-B2 | Polyheterosilxoanes for high refractive index materials | DOW CORNING CORPORATION (US) | 2015-02-24 | — | — | US | disclosed |
| WO-2014152392-A1 | COMPOSITION INCLUDING A POLYHETEROSILOXANE AND AN ORGANOSILOXANE BLOCK COPOLYMER | DOW CORNING CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014152824-A1 | POLYHETEROSILOXANE COMPOSITION AND SILICONE COMPOSITION INCLUDING A POLYHETEROSILOXANE | DOW CORNING CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140135446-A1 | METHODS FOR PREPARING POLYHETEROSILOXANES | DOW CORNING CORPORATION (US) | 2014-05-15 | — | — | US | disclosed |
| US-8674048-B2 | Method for chemically incorporating metal elements into polysiloxanes | DOW CORNING CORPORATION (US) | 2014-03-18 | — | — | US | disclosed |
| WO-2013192404-A1 | POLYHETEROSILOXANE COMPOSITION | DOW CORNING CORPORATION (US) | 2013-12-27 | — | — | WO | disclosed |
| WO-2013192419-A1 | POLYHETEROSILOXANE COMPOSITION | DOW CORNING CORPORATION (US) | 2013-12-27 | — | — | WO | disclosed |
| EP-2661648-A1 | POLYHETEROSILOXANES FOR HIGH REFRACTIVE INDEX MATERIALS | Dow Corning Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| EP-2661647-A1 | POLYHETEROSILOXANES FOR ANTIMICROBIAL MATERIALS | Dow Corning Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130284978-A1 | Polyheterosiloxane Composition Including Lanthanide Metal | DOW CORNING CORPORATION (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2012088439-A1 | POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL | DOW CORNING CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2448999-A1 | METHODS FOR PREPARING POLYHETEROSILOXANES | Dow Corning Corporation (US) | 2012-05-09 | — | — | EP | disclosed |
| US-20120101222-A1 | Method For Chemically Incorporating Metal Elements Into Polysiloxanes | DOW CORNING CORPORATION | 2012-04-26 | — | — | US | disclosed |
| US-7932330-B2 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-26 | — | — | US | disclosed |
| WO-2011002826-A1 | METHODS FOR PREPARING POLYHETEROSILOXANES | DOW CORNING CORPORATION (US) | 2011-01-06 | — | — | WO | disclosed |
| US-7592402-B2 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20080319148-A1 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2008-12-25 | — | — | US | disclosed |
| US-7115539-B2 | Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20050245701-A1 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-11-03 | — | — | US | disclosed |
| US-20040209762-A1 | Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209762-A1 | Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer | AP1M1, PYM1, SEM1 | ESR1 3548/4885ESR2 3623/4885TSHR 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.