SCHEMBL1027104

SCHEMBL1027104

CCO[Si](O)(OCC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
TSHR P16473 2/20 0.34
LTA4H P09960 1/20 0.34
GLA P06280 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 4/20 0.33
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NR1H2 P55055 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19809253 0.90 LMNA (0.38) GAAESR1ESR2TSHRLTA4H
SCHEMBL18043734 0.90 TSHR (0.35) GAAESR1ESR2TSHRLTA4H
Methane SCHEMBL28218846 0.89 LMNA (0.37) GAALTA4HMEN1KMT2ALMNA
SCHEMBL15101559 0.87 LMNA (0.34) GAATSHRMAPTLMNAPIN1
SCHEMBL19809442 0.86 LTA4H (0.41) TSHRLTA4HTP53MEN1KMT2A
SCHEMBL27959421 0.83 EPHX2 (0.34) ESR1ESR2NR1H2NR1H3
SCHEMBL19809355 0.83 LMNA (0.41) GAAESR1ESR2TSHRLTA4H
SCHEMBL14247704 0.82 ESR1 (0.35) GAAESR1ESR2TSHRLTA4H
SCHEMBL1025644 0.82 ESR1 (0.35) GAAESR1ESR2TSHRLTA4H
SCHEMBL28218844 0.82 MAPT (0.33) TSHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
CN-116075368-A Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2023-05-05 CN disclosed
CN-110249004-B Polyimide precursor composition 东京应化工业株式会社 2022-07-19 CN disclosed
CN-108389512-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-04-15 CN disclosed
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed
CN-108387954-B Laminate, flexible device, and method for producing laminate 东京应化工业株式会社 2022-01-18 CN disclosed
CN-107709464-B Silicon-containing resin composition 东京应化工业株式会社 2021-09-28 CN disclosed
CN-112334795-A Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2021-02-05 CN disclosed
CN-107429059-B Energy-sensitive resin composition 东京应化工业株式会社 2020-10-23 CN disclosed
CN-107922733-B Polyimide precursor composition 东京应化工业株式会社 2020-09-11 CN disclosed
US-20130230603-A1 Polyheterosilxoanes For Antimicrobial Materials DOW CORNING CORPORATION (US) 2013-09-05 US disclosed
US-20130230656-A1 Polyheterosilxoanes For High Refractive Index Materials DOW CORNING TORAY CO., LTD. (KR) 2013-09-05 US disclosed
WO-2012094450-A1 POLYHETEROSILOXANES FOR HIGH REFRACTIVE INDEX MATERIALS DOW CORNING CORPORATION (US) 2012-07-12 WO disclosed
WO-2012094457-A1 POLYHETEROSILOXANES FOR ANTIMICROBIAL MATERIALS DOW CORNING CORPORATION (US) 2012-07-12 WO disclosed
WO-2012088439-A1 POLYHETEROSILOXANE COMPOSITION INCLUDING LANTHANIDE METAL DOW CORNING CORPORATION (US) 2012-06-28 WO disclosed
EP-2448999-A1 METHODS FOR PREPARING POLYHETEROSILOXANES Dow Corning Corporation (US) 2012-05-09 EP disclosed
US-20120101222-A1 Method For Chemically Incorporating Metal Elements Into Polysiloxanes DOW CORNING CORPORATION 2012-04-26 US disclosed
WO-2011002826-A1 METHODS FOR PREPARING POLYHETEROSILOXANES DOW CORNING CORPORATION (US) 2011-01-06 WO disclosed
US-6344579-B1 REACTION OF FLUOROSILICON COMPOUND WITH REACTION OF SILICON WITH HYDROXY, ALKOXY OR ARYLOXY GROUP WITH DIFLUORODIAMINO COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-02-05 US disclosed
EP-1138633-A1 PROCESS FOR PRODUCING FLUORINATED SILICON COMPOUND Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130230603-A1 Polyheterosilxoanes For Antimicrobial Materials SCO2, PRXL2A, RIOX2 GAA 1040/4885ESR1 1992/4885ESR2 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.