SCHEMBL10257983

SCHEMBL10257983

Cc1cc(C)c(C2=C(O)[C@H]3[C@@H](C2=O)[C@@H]2CC[C@H]3O2)c(C)c1Br

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
ESR2 Q92731 1/20 0.32
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
PPM1B O75688 1/20 0.30
LMNA P02545 1/20 0.30
PPP1CC P36873 1/20 0.30
TFPI2 P48307 1/20 0.30
RAB9A P51151 1/20 0.30
PPP5C P53041 1/20 0.30
PPP1CA P62136 1/20 0.30
PMP22 Q01453 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
TP53 P04637 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10187541 0.86 L3MBTL1 (0.34) L3MBTL1KDM4EGMNNPPM1BLMNA
SCHEMBL13261980 0.86 L3MBTL1 (0.34) L3MBTL1KDM4EGMNNPPM1BLMNA
SCHEMBL10257452 0.83 L3MBTL1 (0.35) L3MBTL1KDM4EGMNNPPM1BLMNA
SCHEMBL15800430 0.82 ALDH1A1 (0.32) LMNA
SCHEMBL10257698 0.79 KDM4E (0.33) L3MBTL1KDM4ELMNAPPP1CASMN1; SMN2
SCHEMBL15001121 0.78 CNR1 (0.32) L3MBTL1
SCHEMBL10258277 0.78 L3MBTL1 (0.44) L3MBTL1KDM4EGMNNPPM1BLMNA
SCHEMBL10187606 0.77 L3MBTL1 (0.31) L3MBTL1
SCHEMBL10257169 0.77 MAOA (0.32) L3MBTL1LMNASMN1; SMN2
SCHEMBL6727345 0.77 L3MBTL1 (0.39) L3MBTL1LMNATFPI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754242-B2 Herbicides SYNGENTA CROP PROTECTION LLC (US) 2014-06-17 US disclosed
US-8754242-B2 Herbicides SYNGENTA CROP PROTECTION LLC (US) 2014-06-17 US disclosed
US-20120094832-A1 NOVEL HERBICIDES SYNGENTA LIMITED (GB) 2012-04-19 US disclosed
US-20120094832-A1 NOVEL HERBICIDES SYNGENTA LIMITED (GB) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120094832-A1 NOVEL HERBICIDES DDT, CYP1B1, CYP1A1 L3MBTL1 1525/4885ESR2 2024/4885KDM4E 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.