Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025996 | 0.91 | PDE10A (0.35) | PDE10A | |
| SCHEMBL1025104 | 0.89 | PDE10A (0.36) | PDE10A | |
| SCHEMBL1023890 | 0.84 | MEN1 (0.36) | PDE10A | |
| SCHEMBL1025606 | 0.79 | GRM5 (0.38) | — | |
| SCHEMBL2319994 | 0.75 | GABRA1 (0.31) | — | |
| SCHEMBL1026094 | 0.75 | PDE10A (0.39) | PDE10A | |
| SCHEMBL1025108 | 0.75 | PDE10A (0.37) | PDE10A | |
| SCHEMBL1024672 | 0.74 | L3MBTL1 (0.39) | — | |
| SCHEMBL1026639 | 0.73 | PDE10A (0.37) | PDE10A | |
| SCHEMBL1027586 | 0.72 | GRM8 (0.36) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274285-A1 | NOVEL PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2011-01-19 | — | — | EP | claimed |
| WO-2009127612-A1 | NOVEL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | claimed |
| EP-2274285-A1 | NOVEL PYRAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009127612-A1 | NOVEL PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-10-22 | — | — | WO | disclosed |