SCHEMBL10260385

SCHEMBL10260385

O=C1CC(=O)C2=C1CCC2

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
CYP2A6 P11509 1/20 0.35
TRIM24 O15164 2/20 0.33
TRIM33 Q9UPN9 2/20 0.33
UCHL1 P09936 1/20 0.32
UCHL3 P15374 1/20 0.32
ECE1 P42892 1/20 0.32
MUS81 Q96NY9 1/20 0.32
ALDH1A1 P00352 2/20 0.32
PRKCI P41743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10260449 0.93 TRIM24 (0.41) CRBNTRIM24TRIM33UCHL1UCHL3
SCHEMBL14410044 0.79 MAOA (0.40) CRBNMAOAMAOBCYP2A6TRIM24
SCHEMBL7796301 0.72 TRIM24 (0.35) TRIM24TRIM33ALDH1A1
SCHEMBL13140102 0.69 TSHR (0.32)
SCHEMBL11158366 0.68 TSHR (0.32)
SCHEMBL289021 0.68
SCHEMBL5626714 0.67 ALDH1A1 (0.33) CRBNMAOAMAOBCYP2A6TRIM24
SCHEMBL30659949 0.67 TRIM24 (0.44) CRBNMAOAMAOBCYP2A6TRIM24
SCHEMBL10999359 0.67
SCHEMBL5464779 0.65 TRIM24 (0.35) CRBNMAOAMAOBCYP2A6TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383317-B2 Surface treatment of interpenetrating polymer networkcarbon tubes; photolithography; modifying surfaces of carbon nanotubes with polymerizable functional groups such as oxirane and anhydride groups; heat curing; negative patterns SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-02-26 US disclosed
US-8211957-B2 Negative pattern of carbon nanotubes and carbon nanotube composite comprising surface-modified carbon nanotubes SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-07-03 US disclosed
US-7763885-B2 Organic thin film transistor having surface-modified carbon nanotubes SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-07-27 US disclosed
US-20100159219-A1 Negative pattern of carbon nanotubes and carbon nanotube composite comprising surface-modified carbon nanotubes PARK JONG JIN 2010-06-24 US disclosed
US-20090121216-A9 Organic thin film transistor having surface-modified carbon nanotubes SAMSUNG ELECTRONICS CO., LTD. 2009-05-14 US disclosed
US-20080191198-A1 Organic thin film transistor having surface-modified carbon nanotubes SAMSUNG ELECTRONICS CO., LTD. 2008-08-14 US disclosed
US-20080153991-A1 Method of making carbon nanotube patterned film or carbon nanotube composite using carbon nanotubes surface-modified with polymerizable moieties SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100159219-A1 Negative pattern of carbon nanotubes and carbon nanotube composite comprising surface-modified carbon nanotubes ACTN4, NCDN, PNN CRBN 40/4885MAOA 880/4885MAOB 1069/4885
US-20080153991-A1 Method of making carbon nanotube patterned film or carbon nanotube composite using carbon nanotubes surface-modified with polymerizable moieties FSCN1, NCDN, ACTN1 CRBN 42/4885MAOA 314/4885MAOB 513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.