SCHEMBL10261997

SCHEMBL10261997

C1OC1CO[C@H]1COC2C1OC[C@H]2OCC1CO1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.41
▸ ALDH1A1 P00352 8/20 0.39
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TDP1 Q9NUW8 3/20 0.34
▸ TP53 P04637 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ BCHE P06276 3/20 0.32
▸ GLA P06280 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15539608 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL16727813 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL13238229 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15540189 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL817926 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL16727811 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL17212370 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL24419237 0.89 ALDH1A1 (0.38) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15999633 0.89 TSHR (0.39) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL19478755 0.88 ALDH1A1 (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242702-A1 METHOD FOR OBTAINING BIOSOURCED POLYEPOXIDES WITH IMPROVED PROPERTIES ROQUETTE FRERES (FR) 2023-08-03 — — US disclosed
US-20230242702-A1 METHOD FOR OBTAINING BIOSOURCED POLYEPOXIDES WITH IMPROVED PROPERTIES ROQUETTE FRERES (FR) 2023-08-03 — — US disclosed
WO-2022002438-A1 METHOD FOR OBTAINING BIOSOURCED POLYEPOXIDES WITH IMPROVED PROPERTIES ROQUETTE FRERES (FR) 2022-01-06 — — WO disclosed
US-10174152-B2 Process for producing isohexide glycidyl ethers, products thus obtained, and uses thereof ROQUETTE FRERES (FR) 2019-01-08 — — US disclosed
US-9643157-B2 Hydrogel composition NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2017-05-09 — — US disclosed
US-9643157-B2 Hydrogel composition NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2017-05-09 — — US disclosed
US-9605108-B2 Isosorbide-derived epoxy resins and methods of making same NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2017-03-28 — — US disclosed
US-9605108-B2 Isosorbide-derived epoxy resins and methods of making same NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2017-03-28 — — US disclosed
US-20170050172-A1 Hydrogel Composition NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2017-02-23 — — US disclosed
US-20170002132-A1 PROCESS FOR PRODUCING ISOHEXIDE GLYCIDYL ETHERS, PRODUCTS THUS OBTAINED, AND USES THEREOF ROQUETTE FRERES (FR) 2017-01-05 — — US disclosed
US-20170002132-A1 PROCESS FOR PRODUCING ISOHEXIDE GLYCIDYL ETHERS, PRODUCTS THUS OBTAINED, AND USES THEREOF ROQUETTE FRERES (FR) 2017-01-05 — — US disclosed
US-9504987-B2 System and method for superabsorbent material NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2016-11-29 — — US disclosed
US-20150307650-A1 ISOSORBIDE-DERIVED EPOXY RESINS AND METHODS OF MAKING SAME NEW JERSEY INSTITUTE OF TECHNOLOGY 2015-10-29 — — US disclosed
EP-2301941-B1 Isosorbide glyceryl ether derivatives and their use in household applications COGNIS IP MAN GMBH (DE) 2013-06-19 — — EP disclosed
US-8420588-B2 Isosorbide glyceryl ether derivatives and their use in household applications COGNIS IP MANAGEMENT GMBH (DE) 2013-04-16 — — US disclosed
US-8420588-B2 Isosorbide glyceryl ether derivatives and their use in household applications COGNIS IP MANAGEMENT GMBH (DE) 2013-04-16 — — US disclosed
US-20120172282-A1 Isosorbide Glyceryl Ether Derivatives And Their Use In Household Applications COGNIS IP MANAGEMENT GMBH (DE) 2012-07-05 — — US disclosed
US-20120172282-A1 Isosorbide Glyceryl Ether Derivatives And Their Use In Household Applications COGNIS IP MANAGEMENT GMBH (DE) 2012-07-05 — — US disclosed
EP-2301941-A1 Isosorbide glyceryl ether derivatives and their use in household applications Cognis IP Management GmbH (DE) 2011-03-30 — — EP disclosed
WO-2011029548-A1 ISOSORBIDE GLYCERYL ETHER DERIVATIVES AND THEIR USE IN HOUSEHOLD APPLICATIONS COGNIS IP MANAGEMENT GMBH (DE) 2011-03-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242702-A1 METHOD FOR OBTAINING BIOSOURCED POLYEPOXIDES WITH IMPROVED PROPERTIES EPHX2, EPHX1, TET3 TSHR 4774/4885ALDH1A1 176/4885MAPK1 4737/4885
US-10174152-B2 Process for producing isohexide glycidyl ethers, products thus obtained, and uses thereof GALE, DDOST, GYPA TSHR 3974/4885ALDH1A1 3167/4885MAPK1 3897/4885
US-20170002132-A1 PROCESS FOR PRODUCING ISOHEXIDE GLYCIDYL ETHERS, PRODUCTS THUS OBTAINED, AND USES THEREOF GALE, DDOST, GYPA TSHR 3974/4885ALDH1A1 3167/4885MAPK1 3897/4885
US-20120172282-A1 Isosorbide Glyceryl Ether Derivatives And Their Use In Household Applications MGLL, DAGLA, DAGLB TSHR 3856/4885ALDH1A1 1714/4885MAPK1 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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