SCHEMBL13238229

SCHEMBL13238229

C1OC1COC1COC2C(OCC3CO3)COC12

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.41
▸ ALDH1A1 P00352 8/20 0.39
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TDP1 Q9NUW8 3/20 0.34
▸ TP53 P04637 2/20 0.33
▸ CYP3A4 P08684 2/20 0.33
▸ HIF1A Q16665 1/20 0.33
▸ BCHE P06276 3/20 0.32
▸ GLA P06280 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15539608 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL16727813 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15540189 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL817926 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL10261997 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL16727811 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL17212370 1.00 TSHR (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL24419237 0.89 ALDH1A1 (0.38) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15999633 0.89 TSHR (0.39) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL19478755 0.88 ALDH1A1 (0.41) TSHRALDH1A1MAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4464162-A1 COMPOSITIONS FOR EXTENDING THE SHELF LIFE OF A FOOD PRODUCT, METHOD FOR PRODUCING THE COMPOSITIONS, USES THEREOF Agree NET S.r.l. (IT) 2024-11-20 — — EP disclosed
WO-2024046698-A1 EPOXIDE-ALCOHOL-BASED MULTI-COMPONENT RESIN SYSTEM HILTI AKTIENGESELLSCHAFT (LI) 2024-03-07 — — WO disclosed
EP-4332143-A1 MULTICOMPONENT EPOXY-ALCOHOL-BASED RESIN SYSTEM Hilti Aktiengesellschaft (LI) 2024-03-06 — — EP disclosed
WO-2022096148-A1 OLIGOMERIC EPOXY PRE-POLYMERS COMPRISING ISOSORBIDE UNITS ROQUETTE FRERES (FR) 2022-05-12 — — WO disclosed
US-10913817-B2 Use of a composition of low-viscosity bis-anhydrohexitol ethers as a reactive diluent for crosslinkable resin, adhesive, coating and matrix compositions for composites ROQUETTE FRERES (FR) 2021-02-09 — — US disclosed
US-20200262955-A1 Isosorbide derivatives as reactive additives in reactive resins and chemical dowels HILTI AKTIENGESELLSCHAFT (LI) 2020-08-20 — — US disclosed
US-20200123308-A1 USE OF A COMPOSITION OF LOW-VISCOSITY BIS-ANHYDROHEXITOL ETHERS AS A REACTIVE DILUENT FOR CROSSLINKABLE RESIN, ADHESIVE, COATING AND MATRIX COMPOSITIONS FOR COMPOSITES ROQUETTE FRERES (FR) 2020-04-23 — — US disclosed
EP-3489205-A1 ISOSORBIDE DERIVATIVES AS REACTIVE ADDITIVES IN REACTIVE RESINS AND CHEMICAL DOWELS HILTI Aktiengesellschaft (LI) 2019-05-29 — — EP disclosed
US-9156851-B2 Photocurable dianhydro-hexane-hexol derivative, manufacturing method thereof, and photocurable composition including same KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-10-13 — — US disclosed
US-9156851-B2 Photocurable dianhydro-hexane-hexol derivative, manufacturing method thereof, and photocurable composition including same KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-10-13 — — US disclosed
US-20140249285-A1 RENEWABLE BIO-BASED (METH) ACRYLATED MONOMERS AS VINYL ESTER CROSS-LINKERS UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2014-09-04 — — US disclosed
US-20140073716-A1 PHOTOCURABLE DIANHYDRO-HEXANE-HEXOL DERIVATIVE, MANUFACTURING METHOD THEREOF, AND PHOTOCURABLE COMPOSITION INCLUDING SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2014-03-13 — — US disclosed
US-20140073716-A1 PHOTOCURABLE DIANHYDRO-HEXANE-HEXOL DERIVATIVE, MANUFACTURING METHOD THEREOF, AND PHOTOCURABLE COMPOSITION INCLUDING SAME KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2014-03-13 — — US disclosed
WO-2013066461-A2 RENEWABLE BIO-BASED (METH) ACRYLATED MONOMERS AS VINYL ESTER CROSS-LINKERS PALMESE GIUSEPPE R (US) 2013-05-10 — — WO disclosed
US-7754823-B2 Vegetable based dioxanone derivatives, synthesis and uses thereof ARCHER-DANIELS-MIDLAND COMPANY (US) 2010-07-13 — — US disclosed
US-7754823-B2 Vegetable based dioxanone derivatives, synthesis and uses thereof ARCHER-DANIELS-MIDLAND COMPANY (US) 2010-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140073716-A1 PHOTOCURABLE DIANHYDRO-HEXANE-HEXOL DERIVATIVE, MANUFACTURING METHOD THEREOF, AND PHOTOCURABLE COMPOSITION INCLUDING SAME HDHD5, DOHH, HPD TSHR 4815/4885ALDH1A1 410/4885MAPK1 2925/4885
US-20140249285-A1 RENEWABLE BIO-BASED (METH) ACRYLATED MONOMERS AS VINYL ESTER CROSS-LINKERS MACF1, ADH7, CD38 TSHR 3768/4885ALDH1A1 199/4885MAPK1 4708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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