Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15458500 | 0.94 | CCR5 (0.38) | PTPN1GSK3BCDK5CDK5R1CCR5 | |
| SCHEMBL10262086 | 0.91 | CDK5 (0.42) | PTPN1GSK3BCDK5CDK5R1LMNA | |
| SCHEMBL10262247 | 0.89 | GSK3B (0.39) | PTPN1GSK3BCDK5CDK5R1LMNA | |
| SCHEMBL10262730 | 0.87 | SMN1; SMN2 (0.38) | PTPN1GSK3BCDK5CDK5R1LMNA | |
| SCHEMBL10262089 | 0.84 | PDE10A (0.36) | PTPN1GSK3BCDK5CDK5R1LMNA | |
| SCHEMBL15458517 | 0.84 | P2RY12 (0.37) | PTPN1GSK3BCDK5CDK5R1CCR5 | |
| SCHEMBL15458520 | 0.82 | PIK3CD (0.36) | GSK3BCDK5CDK5R1LMNAALDH1A1 | |
| SCHEMBL16301325 | 0.81 | DGAT1 (0.42) | PTPN1ALDH1A1DGAT1PRKDCKDM4E | |
| SCHEMBL15459714 | 0.81 | ATR (0.36) | PTPN1LMNAALDH1A1GAAMAPT | |
| SCHEMBL10293053 | 0.81 | PTPN1 (0.42) | PTPN1LMNAALDH1A1DGAT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691120-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | PTPN1 2542/4885GSK3B 3032/4885CDK5 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.