Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1026657 | 0.99 | NAMPT (0.32) | NAMPTMAPTNPC1CLK1RAB9A | |
| Hydrochloric Acid SCHEMBL1025217 | 0.94 | MAPT (0.32) | NAMPTMAPTNPC1CLK1RAB9A | |
| SCHEMBL1027790 | 0.92 | ACHE (0.34) | MAPTNPC1CLK1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL1197632 | 0.92 | AHCY (0.35) | MAPTNPC1CLK1RAB9ATP53 | |
| Hydrochloric Acid SCHEMBL1197527 | 0.87 | HSD17B1 (0.32) | MAPTNPC1CLK1RAB9AHCRTR1 | |
| Hydrochloric Acid SCHEMBL1027888 | 0.86 | AHCY (0.35) | MAPTNPC1CLK1RAB9A | |
| Hydrochloric Acid SCHEMBL1027430 | 0.86 | PDE4B (0.31) | — | |
| SCHEMBL11974093 | 0.84 | AHCY (0.43) | NAMPTMAPTNPC1CLK1RAB9A | |
| SCHEMBL11974002 | 0.80 | AHCY (0.43) | NAMPTMAPTNPC1CLK1RAB9A | |
| SCHEMBL1028398 | 0.80 | NAMPT (0.36) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |