Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 4/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1197632 | 0.99 | AHCY (0.35) | ACHECLK1NPC1RAB9AAHCY | |
| Hydrochloric Acid SCHEMBL1027888 | 0.93 | AHCY (0.35) | ACHECLK1NPC1RAB9AAHCY | |
| SCHEMBL1026458 | 0.92 | NAMPT (0.33) | CLK1NPC1RAB9AMAPTTP53 | |
| Hydrochloric Acid SCHEMBL1026657 | 0.92 | NAMPT (0.32) | CLK1NPC1RAB9AMAPTTP53 | |
| Hydrochloric Acid SCHEMBL1025217 | 0.86 | MAPT (0.32) | CLK1NPC1RAB9AMAPTTP53 | |
| Hydrochloric Acid SCHEMBL1028342 | 0.85 | AHCY (0.35) | AHCYHSD17B1STS | |
| Hydrochloric Acid SCHEMBL1025666 | 0.85 | AHCY (0.35) | AHCYHSD17B1HSD17B2STS | |
| SCHEMBL11975784 | 0.83 | AHCY (0.51) | ACHECLK1NPC1RAB9AAHCY | |
| Hydrochloric Acid SCHEMBL1028128 | 0.81 | P2RX7 (0.36) | AHCYHSD17B1HSD17B2 | |
| SCHEMBL1197482 | 0.80 | AHCY (0.35) | AHCYMAPTTP53KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |