SCHEMBL1026762

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12708499	0.84	PDE4B (0.50)	PDE4BPDE4APDE4CPDE4DPDE11A
	SCHEMBL27843544	0.80	MCL1 (0.51)	TP53MAPTRAB9ASMN1; SMN2
	SCHEMBL1025742	0.79	RAB9A (0.49)	TP53RAB9ASMN1; SMN2KDM4E
	SCHEMBL1027316	0.77	P2RX1 (0.50)	PDE4BPDE4APDE4CPDE4DP2RX1
	SCHEMBL1665449	0.76	SMN1; SMN2 (0.56)	TP53MAPTRAB9ASMN1; SMN2TYK2
	SCHEMBL1025723	0.76	KDM4E (0.51)	PDE4BPDE4APDE4CPDE4DP2RX1
	SCHEMBL1026305	0.76	KDM4E (0.48)	PDE4BPDE4APDE4CPDE4DP2RX1
	SCHEMBL1027417	0.76	TMPRSS4 (0.56)	P2RX1MAPTSMN1; SMN2JAK2JAK1
	SCHEMBL27843533	0.75	LMNA (0.38)	PDE4BPDE4APDE4CPDE4DLMNA
	SCHEMBL1023011	0.74	KDM4E (0.46)	PDE4BPDE4APDE4CPDE4DP2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.