Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.54 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666242 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2KDM4EALDH1A1HTTTRPV1 | |
| SCHEMBL28636438 | 0.83 | KDM4E (0.74) | SMN1; SMN2KDM4ERORCEPHB3ALDH1A1 | |
| SCHEMBL1025723 | 0.81 | KDM4E (0.51) | SMN1; SMN2KDM4EGRM4MAPTTP53 | |
| SCHEMBL1666253 | 0.81 | HSD17B13 (0.54) | EPHB3GRM4MAPTTYK2RXFP1 | |
| SCHEMBL1026305 | 0.81 | KDM4E (0.48) | SMN1; SMN2KDM4EGRM4MAPTTP53 | |
| SCHEMBL12777742 | 0.80 | RAB9A (0.50) | SMN1; SMN2KDM4EGRM4MAPTTP53 | |
| SCHEMBL1023011 | 0.79 | KDM4E (0.46) | SMN1; SMN2KDM4EGRM4TRPV1MAPT | |
| SCHEMBL5694521 | 0.77 | ALDH1A1 (0.75) | SMN1; SMN2ALDH1A1HTTMAPTTP53 | |
| SCHEMBL1026762 | 0.76 | PDE4B (0.53) | SMN1; SMN2KDM4EGRM4MAPTTP53 | |
| SCHEMBL1027417 | 0.76 | TMPRSS4 (0.56) | SMN1; SMN2TRPV1MAPTTYK2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486035-B1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL CO (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8742112-B2 | Heterocyclic compound and its use for control of an arthropod pest | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-06-03 | — | — | US | disclosed |
| CN-102686585-A | Heterocyclic compound and its use for control of an arthropod pest | SUMITOMO CHEMICAL CO | 2012-09-19 | — | — | CN | disclosed |
| EP-2486035-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | Sumitomo Chemical Co., Ltd (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196891-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-02 | — | — | US | disclosed |
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196891-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | HAAO, DDT, ACHE | SMN1; SMN2 1085/4885KDM4E 1844/4885RORC 2666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.