SCHEMBL10270631

SCHEMBL10270631

Cc1cc(Cl)c2c(n1)/C(=N/OCC1(CO/N=C3\CCCc4c(Cl)cc(C)nc43)CC1)CCC2

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10270637 0.83 L3MBTL1 (0.32) L3MBTL1
SCHEMBL10271153 0.77 L3MBTL1 (0.33) L3MBTL1LMNAMAPTPKM
SCHEMBL10271162 0.74 ALDH1A1 (0.37) LMNAMAPT
SCHEMBL10271360 0.69 L3MBTL1 (0.35) L3MBTL1LMNAMAPTPKM
SCHEMBL10287302 0.69
SCHEMBL10270754 0.68 HTT (0.37) LMNAMAPT
SCHEMBL10270636 0.68
SCHEMBL10271358 0.68 L3MBTL1 (0.34) L3MBTL1LMNAMAPTPKM
SCHEMBL10270635 0.68 RAB9A (0.30)
SCHEMBL10270996 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
WO-2012013754-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES PRDX4, PRDX6, DDT L3MBTL1 773/4885LMNA 4570/4885MAPT 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.