SCHEMBL10270856

SCHEMBL10270856

Cc1ccc2c(n1)/C(=N/OCCCO/N=C1\CCCc3cc4c(nc31)CCCC4)CCC2

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.36
RAB9A P51151 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
GAA P10253 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
PKM P14618 1/20 0.33
NPC1 O15118 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GRM5 P41594 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10271362 0.89 L3MBTL1 (0.37) L3MBTL1RAB9ALMNAMAPTPKM
SCHEMBL10271160 0.89 L3MBTL1 (0.34) L3MBTL1RAB9ALMNAMAPTPKM
SCHEMBL10270625 0.88 L3MBTL1 (0.35) L3MBTL1RAB9ALMNAMAPTGAA
SCHEMBL10270991 0.83 L3MBTL1 (0.32) L3MBTL1RAB9APKM
SCHEMBL15771049 0.83 L3MBTL1 (0.32) L3MBTL1RAB9APKM
SCHEMBL10271155 0.83 LMNA (0.31) L3MBTL1LMNAMAPT
SCHEMBL10271138 0.82 RAB9A (0.33) L3MBTL1RAB9ALMNAMAPTPKM
SCHEMBL10270628 0.81
SCHEMBL10270638 0.80 L3MBTL1 (0.32) L3MBTL1
SCHEMBL10270630 0.78 L3MBTL1 (0.31) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2014-06-12 US disclosed
WO-2012013754-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140162980-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES PRDX4, PRDX6, DDT L3MBTL1 773/4885RAB9A 3345/4885LMNA 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.