Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873197 | 0.88 | EGFR (0.39) | EGFRTYRALOX5PTGS2FFAR1 | |
| SCHEMBL14293919 | 0.87 | TRPV1 (0.39) | EGFRPTGS2KMT2AALDH1A1GAA | |
| SCHEMBL4854736 | 0.84 | EGFR (0.43) | EGFRTYRALOX5PTGS2FFAR1 | |
| SCHEMBL872522 | 0.84 | EGFR (0.43) | EGFRTYRALOX5PTGS2FFAR1 | |
| SCHEMBL328706 | 0.83 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL10272267 | 0.83 | ALOX5 (0.41) | EGFRTYRALOX5PTGS2MAOA | |
| SCHEMBL13013439 | 0.83 | EGFR (0.48) | EGFRTYRALOX5PTGS2FFAR1 | |
| SCHEMBL872574 | 0.80 | EGFR (0.40) | EGFRTYRALOX5PTGS2FFAR1 | |
| SCHEMBL13013000 | 0.80 | FFAR1 (0.43) | EGFRALOX5PTGS2FFAR1MEN1 | |
| SCHEMBL11822461 | 0.79 | ALOX5 (0.43) | EGFRTYRALOX5PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110088595-A1 | PIGMENT PREPARATIONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-04-21 | — | — | US | disclosed |
| WO-1995006651-A1 | HYDROLYTICALLY STABLE PENTAERYTHRITOL DIPHOSPHITES | DOVER CHEMICAL CORPORATION (US) | 1995-03-09 | — | — | WO | disclosed |