Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | WNT3A | P56704 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758861 | 0.85 | CES2 (0.69) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL1712437 | 0.84 | CES2 (0.67) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL2073691 | 0.84 | ACHE (0.72) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL2379125 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL716488 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL31016229 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL29742875 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL311526 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL40175 | 0.82 | CES2 (0.65) | CES2SRD5A2CTNNB1WNT3APOLB | |
| SCHEMBL2096484 | 0.82 | CES2 (0.70) | CES2SRD5A2CTNNB1WNT3APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006475-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-01-12 | — | — | WO | disclosed |