Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11896239 | 0.89 | AHCY (0.41) | AHCYMAPTTP53 | |
| SCHEMBL1196560 | 0.87 | MAPT (0.36) | MAPTTP53ALDH1A1SMN1; SMN2GSTP1 | |
| SCHEMBL1198040 | 0.80 | AHCY (0.42) | AHCYMAPTTP53ALDH1A1LMNA | |
| SCHEMBL11903758 | 0.80 | AHCY (0.45) | AHCY | |
| SCHEMBL11974832 | 0.80 | AHCY (0.44) | AHCYMAPTTP53ALDH1A1LMNA | |
| SCHEMBL1026964 | 0.79 | MAPT (0.37) | AHCYMAPTTP53 | |
| SCHEMBL11956116 | 0.78 | LMNA (0.38) | AHCYMAPTLMNATSHR | |
| SCHEMBL1196372 | 0.77 | AHCY (0.45) | AHCYMAPTLMNATSHR | |
| SCHEMBL1026232 | 0.77 | AHCY (0.45) | AHCY | |
| SCHEMBL1027797 | 0.77 | AHCY (0.45) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486925-A1 | THERAPEUTIC AGENT FOR CEREBRAL INFARCTION | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |