Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186288 | 1.00 | PAOX (0.61) | PAOXSMN1; SMN2ALDH1A1SLC6A5MAOA | |
| SCHEMBL8351641 | 0.98 | PAOX (0.58) | PAOXSMN1; SMN2ALDH1A1SLC6A5MAOA | |
| SCHEMBL24611784 | 0.93 | ALDH1A1 (0.59) | PAOXSMN1; SMN2ALDH1A1HIF1AMEN1 | |
| SCHEMBL14198854 | 0.93 | ALDH1A1 (0.59) | PAOXSMN1; SMN2ALDH1A1HIF1AMEN1 | |
| SCHEMBL1886044 | 0.90 | — | — | |
| SCHEMBL16853212 | 0.90 | ALDH1A1 (0.55) | PAOXSMN1; SMN2ALDH1A1HIF1AMEN1 | |
| SCHEMBL9062908 | 0.86 | PAOX (0.61) | PAOXSMN1; SMN2ALDH1A1SLC6A5MAOA | |
| SCHEMBL12660515 | 0.85 | MEN1 (0.48) | PAOXSMN1; SMN2ALDH1A1HIF1AMEN1 | |
| SCHEMBL6255247 | 0.85 | CA12 (0.54) | PAOXSMN1; SMN2MEN1KMT2ACASP2 | |
| SCHEMBL7208464 | 0.84 | SLC6A5 (0.67) | PAOXSMN1; SMN2ALDH1A1SLC6A5HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765934-B2 | Methods for conjugating nucleic acids with small molecules | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-07-01 | — | — | US | disclosed |
| US-20120177573-A1 | METHODS FOR CONJUGATING NUCLEIC ACIDS WITH SMALL MOLECULES | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177573-A1 | METHODS FOR CONJUGATING NUCLEIC ACIDS WITH SMALL MOLECULES | RNGTT, POLM, POLRMT | PAOX 1530/4885SMN1; SMN2 2853/4885ALDH1A1 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.