SCHEMBL1027787

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1025838	0.87	TRPV1 (0.39)	SMN1; SMN2NPC1RAB9AALDH1A1MAPT
	SCHEMBL1026791	0.86	P2RX1 (0.36)	CYP1A2GPBAR1SMN1; SMN2NPC1RAB9A
	SCHEMBL1025360	0.86	S1PR1 (0.46)	CYP1A2METAP2GPBAR1SMN1; SMN2NPC1
	SCHEMBL1025778	0.86	ALDH1A1 (0.42)	SMN1; SMN2NPC1RAB9AALDH1A1MAPT
	SCHEMBL4544499	0.83	F7 (0.40)	CYP1A2F7F3F10NUDT1
	SCHEMBL1026573	0.83	KDM4E (0.38)	CYP1A2METAP2SMN1; SMN2NPC1RAB9A
	SCHEMBL1023816	0.83	SGMS2 (0.38)	GPBAR1S1PR1PDE2APDE7APDE10A
	SCHEMBL1023296	0.83	CYP1A2 (0.46)	CYP1A2METAP2GPBAR1SMN1; SMN2RAB9A
	SCHEMBL1554514	0.83	ALDH1A1 (0.36)	CYP1A2METAP2GPBAR1SMN1; SMN2NPC1
	SCHEMBL12693240	0.82	PTGS2 (0.36)	CYP1A2METAP2GPBAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.