Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280395 | 0.91 | DHODH (0.37) | DHODHMALT1DGAT2KMT2A | |
| SCHEMBL10280352 | 0.90 | DHODH (0.40) | DHODHMALT1DGAT2 | |
| SCHEMBL10280390 | 0.89 | KLKB1 (0.34) | MALT1DGAT2 | |
| SCHEMBL10280536 | 0.87 | DGAT2 (0.34) | DHODHMALT1DGAT2 | |
| SCHEMBL4168969 | 0.85 | DHODH (0.41) | DHODHMALT1DGAT2NTRK1 | |
| SCHEMBL950846 | 0.84 | DHODH (0.44) | DHODHMALT1NTRK1DRD4F10 | |
| SCHEMBL14470469 | 0.84 | MALT1 (0.31) | DHODHMALT1DGAT2 | |
| Chlorantraniliprole SCHEMBL29551 | 0.83 | DHODH (0.44) | DHODHMALT1NTRK1DRD4F10 | |
| Chlorantraniliprole SCHEMBL29363261 | 0.83 | DHODH (0.44) | DHODHMALT1NTRK1DRD4F10 | |
| SCHEMBL10280531 | 0.83 | DHODH (0.40) | DHODHMALT1DGAT2SMONTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2007080131-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | SYNGENTA PARTICIPATIONS AG (CH) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077991-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | DHODH 138/4885MALT1 3570/4885DGAT2 661/4885 |
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | DHODH 155/4885MALT1 3566/4885DGAT2 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.