Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168969 | 0.91 | DHODH (0.41) | DHODHMALT1NTRK1DGAT2TRPV1 | |
| SCHEMBL10279971 | 0.91 | DHODH (0.38) | DHODHMALT1 | |
| SCHEMBL10280533 | 0.89 | MALT1 (0.33) | DHODHMALT1NTRK1F9 | |
| SCHEMBL10279969 | 0.89 | KLKB1 (0.34) | MALT1TRPV1 | |
| SCHEMBL10280352 | 0.88 | DHODH (0.40) | DHODHMALT1DGAT2 | |
| SCHEMBL10280398 | 0.86 | DGAT2 (0.34) | DHODHMALT1NTRK1DGAT2TRPV1 | |
| SCHEMBL12912066 | 0.85 | DHODH (0.44) | DHODHMALT1TRPV1 | |
| SCHEMBL4162046 | 0.85 | DHODH (0.39) | DHODHMALT1NTRK1DGAT2 | |
| Chlorantraniliprole SCHEMBL29551 | 0.84 | DHODH (0.44) | DHODHMALT1NTRK1TRPV1 | |
| Chlorantraniliprole SCHEMBL29363261 | 0.84 | DHODH (0.44) | DHODHMALT1NTRK1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2007080131-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | SYNGENTA PARTICIPATIONS AG (CH) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077991-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | DHODH 138/4885MALT1 3570/4885NTRK1 2461/4885 |
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | DHODH 155/4885MALT1 3566/4885NTRK1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.