Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10280398 | 0.90 | DGAT2 (0.34) | TRPV1MALT1 | |
| SCHEMBL867724 | 0.90 | TRPV1 (0.34) | KLKB1TRPV1MALT1PDE4BOPRL1 | |
| SCHEMBL10239581 | 0.89 | DGAT2 (0.37) | TRPV1MALT1 | |
| SCHEMBL10280397 | 0.89 | DHODH (0.39) | TRPV1MALT1 | |
| SCHEMBL10279935 | 0.88 | DGAT2 (0.34) | TRPV1MALT1PDE4BF10CARM1 | |
| SCHEMBL10280533 | 0.88 | MALT1 (0.33) | MALT1PDE4B | |
| SCHEMBL3679335 | 0.86 | PDE4B (0.37) | KLKB1TRPV1MALT1PDE4BF10 | |
| SCHEMBL10239597 | 0.86 | CRHR1 (0.36) | KLKB1TRPV1MALT1OPRL1 | |
| SCHEMBL10239587 | 0.86 | KLKB1 (0.37) | KLKB1F10CARM1 | |
| SCHEMBL782368 | 0.85 | CARM1 (0.39) | KLKB1TRPV1MALT1PDE4BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213167-B1 | Anthranilamide derivatives and their use for the control of insects and acari | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| US-8278464-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120077991-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, LLC | 2012-03-29 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084474-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168066-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2007080131-A2 | ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI | SYNGENTA PARTICIPATIONS AG (CH) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077991-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | KLKB1 4683/4885TRPV1 962/4885MALT1 3570/4885 |
| US-20100168066-A1 | NOVEL INSECTICIDES | DDT, ACHE, CYP4F11 | KLKB1 4570/4885TRPV1 1289/4885MALT1 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.