SCHEMBL10280703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16283878	0.91	ALDH1A1 (0.44)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL15427236	0.83	ALOX5AP (0.42)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL16666988	0.76	L3MBTL1 (0.48)	ALDH1A1SMN1; SMN2KDM4EDDR1L3MBTL1
	SCHEMBL10281005	0.76	ALOX5AP (0.43)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL15426441	0.76	ALOX5AP (0.41)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL9959573	0.75	KDM4E (0.38)	NPC1ALDH1A1SMN1; SMN2KDM4EHPGD
	SCHEMBL9635775	0.74	KDM4E (0.53)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL10739495	0.74	NPC1 (0.49)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A
	SCHEMBL9959388	0.73	PDE2A (0.35)	NPC1ALDH1A1SMN1; SMN2KDM4EHPGD
	SCHEMBL16666271	0.73	KDM4E (0.39)	NPC1ALDH1A1SMN1; SMN2KDM4EPDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.