Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411763 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2APTGS1CA1 | |
| SCHEMBL411360 | 0.77 | POLB (0.39) | SMN1; SMN2LMNAALDH1A1MEN1MAPT | |
| SCHEMBL412435 | 0.76 | PTGS2 (0.36) | ALDH1A1MEN1KMT2APTGS1CA1 | |
| SCHEMBL412761 | 0.73 | ALDH1A1 (0.32) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL10281195 | 0.63 | MAPK1 (0.42) | SMN1; SMN2ALDH1A1BRD4HSD17B10MEN1 | |
| SCHEMBL5539530 | 0.60 | KMT2A (0.51) | TP53SMN1; SMN2LMNABRD4HSD17B10 | |
| SCHEMBL2435451 | 0.60 | NPC1 (0.33) | LMNAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12930022 | 0.60 | CYP2C9 (0.43) | SMN1; SMN2MEN1KMT2APTGS1CA1 | |
| SCHEMBL350060 | 0.59 | NPC1 (0.35) | LMNAALDH1A1BRD4KMT2AHPGD | |
| SCHEMBL24535435 | 0.59 | CYP11B2 (0.37) | SMN1; SMN2LMNAALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009698-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBOTT LABORATORIES (US) | 2012-01-19 | — | — | WO | disclosed |