Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412304 | 0.78 | KDM1A (0.32) | — | |
| SCHEMBL24535424 | 0.76 | TDP2 (0.33) | NPC1RAB9AALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL350060 | 0.74 | NPC1 (0.35) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL9479178 | 0.74 | OPRM1 (0.32) | — | |
| SCHEMBL24535419 | 0.72 | MEN1 (0.41) | ALDH1A1CYP1A2MEN1KMT2AMAPT | |
| SCHEMBL24535435 | 0.71 | CYP11B2 (0.37) | ALDH1A1CYP2C9CYP1A2CYP2C19LMNA | |
| SCHEMBL10177360 | 0.70 | BRD4 (0.35) | NPC1RAB9AALDH1A1LMNAMEN1 | |
| SCHEMBL365324 | 0.70 | ALDH1A1 (0.37) | ALDH1A1CYP2C9CYP1A2CYP2C19LMNA | |
| SCHEMBL411360 | 0.69 | POLB (0.39) | NPC1RAB9AALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL19207380 | 0.68 | ALDH1A1 (0.33) | ALDH1A1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132048-A1 | PHOSPHORUS COMPOUNDS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-06-23 | — | — | WO | disclosed |
| US-20120269872-A1 | NOVEL SALT 628 | ASTRAZENECA AB (SE) | 2012-10-25 | — | — | US | disclosed |
| US-8232296-B2 | Salt 628 | ASTRAZENECA AB (SE) | 2012-07-31 | — | — | US | disclosed |
| EP-2398792-A1 | TOSYLATE SALT OF A 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE, USEFUL IN THE TREATMENT OF COPD | AstraZeneca AB (SE) | 2011-12-28 | — | — | EP | disclosed |
| WO-2011110852-A1 | POLYMORPHIC FORMS OF 6- [2- (4 -CYANOPHENYL) - 2H - PYRAZOL - 3 - YL] - 5 -METHYL - 3 - OXO - 4 - (TRIFLUOROMETHYL - PHENYL) 3,4-DIHYDROPYRAZINE-2-CARBOXYLIC ACID ETHYLAMIDE | ASTRAZENECA AB (SE) | 2011-09-15 | — | — | WO | disclosed |
| US-20110224229-A1 | Novel Crystalline Form | ASTRAZENECA AB (SE) | 2011-09-15 | — | — | US | disclosed |
| US-20100216843-A1 | NOVEL SALT 628 | ASTRAZENECA R&D | 2010-08-26 | — | — | US | disclosed |
| WO-2010094964-A1 | TOSYLATE SALT OF A 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE, USEFUL IN THE TREATMENT OF COPD | ASTRAZENECA AB (SE) | 2010-08-26 | — | — | WO | disclosed |
| EP-1296992-B1 | PHOSPHACYCLOHEXANES AND THE USE THEREOF IN THE HYDROFORMYLATION OF OLEFINS | BASF SE (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1296992-B1 | PHOSPHACYCLOHEXANES AND THE USE THEREOF IN THE HYDROFORMYLATION OF OLEFINS | BASF SE (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-7012162-B2 | ccomplexes with transition metal; hydrogenation catalyst | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-14 | — | — | US | disclosed |
| US-20040106512-A1 | ccomplexes with transition metal; hydrogenation catalyst | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-03 | — | — | US | disclosed |
| EP-0145650-B1 | 1H-POLYALKYL-PHOSPHORINANES | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |
| US-4642382-A | OIL ADDITIVES, POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |
| US-4539421-A | HEAT, LIGHT AND OXIDATION STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0145650-A1 | 1H-polyalkyl-phosphorinanes | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224229-A1 | Novel Crystalline Form | UACA, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC1 | NPC1 274/4885RAB9A 2617/4885ALDH1A1 2432/4885 |
| US-20120269872-A1 | NOVEL SALT 628 | REN, SCN8A, SLC38A7 | NPC1 1617/4885RAB9A 678/4885ALDH1A1 3387/4885 |
| US-20100216843-A1 | NOVEL SALT 628 | REN, SCN8A, SLC38A7 | NPC1 1603/4885RAB9A 653/4885ALDH1A1 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.