SCHEMBL10280992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10280731	0.87	HSD11B1 (0.38)	USP1SMN1; SMN2ALOX5APFEN1BRD4
	SCHEMBL10280794	0.87	LMNA (0.38)	LMNAHTTSMN1; SMN2ALOX5APFEN1
	SCHEMBL14677115	0.86	LMNA (0.38)	USP1LMNAHTTSMN1; SMN2POLB
	SCHEMBL29431631	0.86	LMNA (0.38)	USP1LMNAHTTSMN1; SMN2POLB
	SCHEMBL15412773	0.86	BRD4 (0.40)	USP1ALOX5APFEN1BRD4ATR
	SCHEMBL15412012	0.85	POLB (0.46)	USP1LMNAHTTALOX5APFEN1
	SCHEMBL10281048	0.83	POLB (0.38)	USP1LMNAHTTALOX5APFEN1
	SCHEMBL10280704	0.82	USP1 (0.38)	USP1ALOX5APFEN1POLBBRD4
	SCHEMBL10280998	0.82	USP1 (0.39)	USP1ALOX5APFEN1POLBPDE2A
	SCHEMBL15426276	0.82	BRD4 (0.38)	USP1LMNAHTTSMN1; SMN2ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.