Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952117 | 0.86 | MAPK1 (0.54) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL15412709 | 0.81 | MAPK1 (0.45) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL15427212 | 0.74 | HSD17B10 (0.51) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL9952288 | 0.72 | RXFP1 (0.48) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL15412711 | 0.66 | ALOX15 (0.34) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL27914887 | 0.66 | L3MBTL1 (0.53) | ALDH1A1L3MBTL1MAPTLMNAKDM4E | |
| SCHEMBL17286442 | 0.65 | MAPK1 (0.62) | MAPK1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL20708654 | 0.64 | NOS3 (0.37) | — | |
| SCHEMBL25468268 | 0.63 | CHRNA7 (0.32) | HSD17B10ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL18624697 | 0.63 | MAPK1 (0.56) | MAPK1ALOX15HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655337-B1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-11-23 | — | — | EP | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |