Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 4/20 | 0.32 |
| ▸ | AHCY | P23526 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1071904 | 0.99 | RXRA (0.36) | RXRARXRBRXRGNPSR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL1029811 | 0.85 | AHCY (0.37) | ACKR3AHCY | |
| Hydrochloric Acid SCHEMBL1026875 | 0.84 | AHCY (0.36) | ACKR3AHCYMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1028279 | 0.83 | KDM4E (0.35) | MAPTALDH1A1ACKR3AHCYMEN1 | |
| SCHEMBL1026715 | 0.82 | AHCY (0.42) | MAPTAHCYMEN1KMT2A | |
| SCHEMBL1024510 | 0.81 | MMP1 (0.34) | ACKR3AHCY | |
| SCHEMBL1026778 | 0.81 | TAS1R3 (0.39) | ALDH1A1ACKR3AHCY | |
| SCHEMBL1028041 | 0.81 | AHCY (0.32) | ACKR3AHCY | |
| Hydrochloric Acid SCHEMBL1028159 | 0.81 | AHCY (0.42) | MAPTALDH1A1AHCYMEN1KMT2A | |
| SCHEMBL1025802 | 0.81 | AHCY (0.32) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |