Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | TGM1 | P22735 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028213 | 1.00 | KMT2A (0.55) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL28057964 | 0.88 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL15915623 | 0.81 | RECQL (0.53) | — | |
| SCHEMBL12619908 | 0.81 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL6199063 | 0.81 | KMT2A (0.57) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL6199054 | 0.81 | KMT2A (0.57) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL454129 | 0.79 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL31690564 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL4371394 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1CA1CA2 | |
| SCHEMBL30649118 | 0.79 | KMT2A (0.71) | KMT2AMEN1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513235-B2 | Homocysteine synthase inhibitor | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-02-10 | — | — | US | disclosed |
| EP-2275404-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034440-A1 | HOMOCYSTEINE SYNTHASE INHIBITOR | BHMT, CBS, BHMT2 | KMT2A 1006/4885MEN1 514/4885ALDH1A1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.