Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031916 | 0.95 | NPSR1 (0.51) | CACNA1GEEF2KNPSR1 | |
| SCHEMBL1031140 | 0.85 | NPSR1 (0.49) | CACNA1GNPSR1MEN1KMT2A | |
| SCHEMBL1031841 | 0.81 | NPSR1 (0.47) | CACNA1GNPSR1MEN1KMT2A | |
| SCHEMBL1033446 | 0.78 | NPC1 (0.53) | MEN1KMT2A | |
| SCHEMBL1081685 | 0.77 | NPSR1 (0.60) | CACNA1GNPSR1MEN1KMT2A | |
| SCHEMBL1031909 | 0.76 | NPC1 (0.47) | NPSR1MEN1KMT2AFAAHACHE | |
| SCHEMBL2638817 | 0.76 | NOTUM (0.48) | — | |
| SCHEMBL1032145 | 0.76 | EPHX2 (0.45) | NPSR1 | |
| SCHEMBL1031907 | 0.75 | HTT (0.55) | KMT2A | |
| SCHEMBL1031517 | 0.74 | KDM4E (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |