Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030647 | 0.83 | HTT (0.59) | KMT2AALDH1A1TSHRL3MBTL1RECQL | |
| SCHEMBL1031916 | 0.83 | NPSR1 (0.51) | NPSR1CACNA1GTSHR | |
| SCHEMBL1031140 | 0.81 | NPSR1 (0.49) | NPSR1KMT2AMEN1CACNA1GALDH1A1 | |
| SCHEMBL1031613 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TSHRPOLB | |
| SCHEMBL1031841 | 0.80 | NPSR1 (0.47) | NPSR1KMT2AMEN1CACNA1GALDH1A1 | |
| SCHEMBL1028264 | 0.77 | CACNA1G (0.47) | NPSR1KMT2AMEN1CACNA1G | |
| SCHEMBL279945 | 0.76 | NPSR1 (0.97) | NPSR1KMT2AMEN1CACNA1GALDH1A1 | |
| SCHEMBL1030747 | 0.76 | NPC1 (0.53) | KMT2A | |
| SCHEMBL10195008 | 0.75 | NPSR1 (0.94) | NPSR1KMT2AMEN1CACNA1GALDH1A1 | |
| SCHEMBL1031804 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |