Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031916 | 0.87 | NPSR1 (0.51) | NPSR1CACNA1GTSHR | |
| SCHEMBL1031140 | 0.83 | NPSR1 (0.49) | NPSR1CACNA1GALDH1A1TSHRMEN1 | |
| SCHEMBL1029020 | 0.83 | KDM4E (0.39) | NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1028264 | 0.81 | CACNA1G (0.47) | NPSR1CACNA1GMEN1KMT2A | |
| SCHEMBL1081685 | 0.80 | NPSR1 (0.60) | NPSR1CACNA1GALDH1A1TSHRRECQL | |
| SCHEMBL1030646 | 0.78 | LMNA (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2637992 | 0.78 | SLC22A12 (0.46) | NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1032465 | 0.77 | TP53 (0.42) | NPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL1031907 | 0.74 | HTT (0.55) | ALDH1A1TSHRKMT2A | |
| SCHEMBL1032679 | 0.73 | RORC (0.44) | NPSR1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035375-B1 | 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2011-01-19 | — | — | EP | claimed |