Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595709 | 0.82 | PTGS2 (0.51) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL6765848 | 0.81 | PTGS2 (0.51) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7384646 | 0.81 | LMNA (0.40) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL11434977 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL7721146 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL11443812 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9428564 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9560125 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9428247 | 0.79 | HDAC1 (0.46) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9428037 | 0.79 | PTGS2 (0.52) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |