Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765848 | 0.95 | PTGS2 (0.51) | PTGS2TLR8LMNAMEN1THRB | |
| SCHEMBL11434977 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL9428037 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL11443812 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL7721146 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL9428564 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL9560125 | 0.93 | PTGS2 (0.52) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL7760109 | 0.89 | PTGS2 (0.47) | PTGS2LMNAMEN1THRBBLM | |
| SCHEMBL7318590 | 0.84 | PTGS2 (0.49) | PTGS2TLR8LMNAMEN1KMT2A | |
| SCHEMBL16706971 | 0.83 | PTGS2 (0.50) | PTGS2EPHX2CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243159-A9 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-07-31 | — | — | US | disclosed |
| US-20240383847-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-11-21 | — | — | US | disclosed |
| EP-4452933-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | Massachusetts Institute of Technology (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118679145-A | Biomolecule-polymer-agent conjugates for delivery of agents | 麻省理工学院 | 2024-09-20 | — | — | CN | disclosed |
| US-12084415-B2 | Biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2023121753-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-06-29 | — | — | WO | disclosed |
| US-20230192610-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-06-22 | — | — | US | disclosed |
| EP-0572712-B1 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5298630-A | Reacting 2-alkylthiobenzaldehyde derivative with halo compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0572712-A2 | Processes for producing 2-substituted benzo(beta)thiophene | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4031104-A | ANTIHYPERTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-21 | — | — | US | disclosed |
| US-4020178-A | 1,4-Dihydropyridine esters used as coronary dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-26 | — | — | US | disclosed |
| US-3996234-A | CORONARY VESSEL DILATORS, HYPOTENSIVES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |
| US-3974278-A | 1,4-Dihydropyridine esters | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3974275-A | 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3971796-A | 1,4-Dihydropyridine esters | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |
| US-3966948-A | Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
| US-3946028-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946027-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3943140-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383847-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MUC1, APOB, PLTP | PTGS2 3942/4885TLR8 406/4885LMNA 321/4885 |
| US-20230192610-A1 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MUC1, APOB, PLTP | PTGS2 3942/4885TLR8 406/4885LMNA 321/4885 |
| US-12084415-B2 | Biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent | MUC1, APOB, PLTP | PTGS2 3942/4885TLR8 406/4885LMNA 321/4885 |
| US-20250243159-A9 | BIOMOLECULE-POLYMER-PHARMACEUTICAL AGENT CONJUGATES FOR DELIVERING THE PHARMACEUTICAL AGENT | MUC1, APOB, PLTP | PTGS2 3942/4885TLR8 406/4885LMNA 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.