Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of 4-Aminophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | THRB | P10828 | 3/20 | 0.72 |
| ▸ | CASP1 | P29466 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA6 | P23280 | 2/20 | 0.72 |
| ▸ | CA3 | P07451 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Aminophenol SCHEMBL17436623 | 1.00 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| 4-Aminophenol SCHEMBL27327366 | 0.92 | ALDH1A1 (0.68) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL147074 | 0.88 | TSHR (0.68) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL28572498 | 0.88 | TSHR (0.68) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL28270834 | 0.88 | TSHR (0.68) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| 4-Aminophenol SCHEMBL22462461 | 0.86 | ALDH1A1 (0.68) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Hydroquinone SCHEMBL9458925 | 0.85 | TSHR (0.82) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL28964013 | 0.85 | TSHR (0.65) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL1599590 | 0.85 | TSHR (0.65) | ALDH1A1CYP3A4ALOX15HSD17B10THRB | |
| Sulfuric Acid SCHEMBL27972059 | 0.85 | TSHR (0.65) | ALDH1A1CYP3A4ALOX15HSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638280-A | Novel polymerized monomer, curing method thereof and solid-state battery | 苏州钠绪新能源科技有限公司 | 2024-09-13 | — | — | CN | claimed |
| EP-4424365-A2 | PET FOOD COMPOSITIONS | Hill's Pet Nutrition, Inc. (US) | 2024-09-04 | — | — | EP | claimed |
| EP-4017281-B1 | PET FOOD COMPOSITIONS | HILLS PET NUTRITION INC (US) | 2024-08-28 | — | — | EP | claimed |
| EP-3634365-B1 | HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE | HENKEL AG & CO KGAA (DE) | 2022-08-10 | — | — | EP | claimed |
| CN-114828648-A | Pet food compositions | 希尔氏宠物营养品公司 | 2022-07-29 | — | — | CN | claimed |
| EP-4017281-A1 | PET FOOD COMPOSITIONS | Hill's Pet Nutrition, Inc. (US) | 2022-06-29 | — | — | EP | claimed |
| WO-2021127701-A1 | PET FOOD COMPOSITIONS | HILL'S PET NUTRITION, INC. (US) | 2021-06-24 | — | — | WO | claimed |
| CN-112812025-A | Preparation process of p-aminophenol | 江苏普洛德化学科技有限公司 | 2021-05-18 | — | — | CN | claimed |
| EP-3496818-B1 | PROCESS FOR PREPARING HAIR DYE AGENTS HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES | HENKEL AG & CO KGAA (DE) | 2021-01-20 | — | — | EP | claimed |
| US-10736827-B2 | Hair dye agent having unilamellar and multilamellar vesicles | HENKEL AG & CO. KGAA (DE) | 2020-08-11 | — | — | US | claimed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | claimed |
| EP-1429715-A2 | HAIR COLOURING COMPOSITIONS | The Boots Company PLC (GB) | 2004-06-23 | — | — | EP | claimed |
| US-6702863-B1 | SINGLE PACKAGE AEROSOL CONPRISED OF 5,6-DIHYDROXYINDOLINE, LACCASE, WATER AND PROPELLANT; NONIRRITATING; STORAGE STABLE | LION CORPORATION (JP) | 2004-03-09 | — | — | US | claimed |
| WO-2003015734-A2 | HAIR COLOURING COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2003-02-27 | — | — | WO | claimed |
| US-5942216-A | COMPRISING AN EXTERNAL AQUEOUS PHASE OF A SURFACTANT CAPABLE OF FORMIG LIQUID CRYSTALS AS AN EMULSIFIER; THE INTERNAL WATER-IN OIL EMULSION HAVING A TOPICALLY-ACTIVE COMPOUND AND SURFACTANT AND OIL PHASES; HAIR AND SKIN TREATMENTS | HELENE CURTIS, INC. (US) | 1999-08-24 | — | — | US | claimed |
| CN-1116089-A | Natural tea black hair dying agent and making method thereof | HE WEIHUA (CN) | 1996-02-07 | — | — | CN | claimed |
| EP-0160562-B1 | PROCESS FOR THE CONTINUOUS PREPARATION OF P-PHENYLENEDIAMINE FROM A NITROBENZENE FEEDSTOCK | Montvale Process Company Incorporated (US) | 1990-03-28 | — | — | EP | claimed |
| EP-0160562-A1 | Process for the continuous preparation of P-phenylenediamine from a nitrobenzene feedstock | Montvale Process Company Incorporated (US) | 1985-11-06 | — | — | EP | claimed |
| US-4427762-A | DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-01-24 | — | — | US | claimed |
| EP-0082015-A1 | Method of forming an image with a photographic cuprous halide material | KONICA CORPORATION (JP) | 1983-06-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736827-B2 | Hair dye agent having unilamellar and multilamellar vesicles | EXOSC10, ANXA5, ANXA4 | ALDH1A1 579/4885CYP3A4 1936/4885ALOX15 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.