Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426255 | 0.78 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9ATYK2CYP3A4 | |
| SCHEMBL30331009 | 0.78 | CYP19A1 (0.61) | L3MBTL1NPC1RAB9ATYK2CYP3A4 | |
| SCHEMBL8864603 | 0.76 | L3MBTL1 (0.65) | L3MBTL1NPC1RAB9ATYK2CYP3A4 | |
| SCHEMBL9524288 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ATYK2CYP3A4 | |
| SCHEMBL9524284 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ATYK2CYP3A4 | |
| SCHEMBL6473034 | 0.72 | RAB9A (0.50) | L3MBTL1NPC1RAB9ACYP3A4CYP2C19 | |
| SCHEMBL8508169 | 0.72 | HPGD (0.44) | MAPK1HPGDELANE | |
| SCHEMBL27832641 | 0.72 | HPGD (0.44) | MAPK1HPGDELANE | |
| SCHEMBL6446499 | 0.72 | ERCC5 (0.41) | NPC1RAB9AALDH1A1KMT2AHPGD | |
| SCHEMBL24505933 | 0.70 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9ATYK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |