Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 5/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 5/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285543 | 0.83 | TEAD1 (0.50) | ERCC1ERCC4DRD4TEAD1ACHE | |
| SCHEMBL13573575 | 0.82 | LTA4H (0.52) | LTA4HDRD4TEAD1MAPTPDCD1LG2 | |
| SCHEMBL109025 | 0.81 | ERCC1 (0.53) | ERCC1ERCC4MAPTKDM4EALDH1A1 | |
| SCHEMBL13868598 | 0.81 | ERCC1 (0.53) | ERCC1ERCC4MAPTKDM4EALDH1A1 | |
| SCHEMBL13911887 | 0.81 | BCHE (0.56) | LTA4HTEAD1MAPTOPRL1KDM4E | |
| SCHEMBL29238649 | 0.80 | DRD4 (0.61) | LTA4HDRD4MAPTACHEBACE1 | |
| SCHEMBL15587408 | 0.80 | ACHE (0.63) | LTA4HDRD4TEAD1ACHEBACE1 | |
| SCHEMBL11999842 | 0.80 | LTA4H (0.52) | LTA4HMAPTKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6538885 | 0.80 | BCHE (0.54) | LTA4HTEAD1MAPTOPRL1KDM4E | |
| SCHEMBL19008157 | 0.77 | DRD4 (0.49) | LTA4HDRD4TEAD1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |