SCHEMBL10286100

SCHEMBL10286100

C#CCOc1cc(C)nc2c1CCCCC2=O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
MAOB P27338 4/20 0.33
MAOA P21397 3/20 0.33
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
PGK1 P00558 1/20 0.32
POLB P06746 3/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10286493 0.97 L3MBTL1 (0.36) L3MBTL1MAOBMAOAKMT2AKDM4E
SCHEMBL10286121 0.83 RXFP1 (0.42) L3MBTL1KMT2AKDM4EALDH1A1TSHR
SCHEMBL10286444 0.81 RXFP1 (0.39) L3MBTL1KMT2AKDM4EALDH1A1GAA
SCHEMBL10286127 0.79 MAPT (0.36) KMT2AKDM4EALDH1A1GAATSHR
SCHEMBL10286171 0.79 ALDH1A1 (0.44) KMT2AKDM4EALDH1A1GLAGAA
SCHEMBL10286508 0.76 ALDH1A1 (0.36) KMT2AKDM4EALDH1A1GAATSHR
SCHEMBL10286891 0.76 UGCG (0.40) L3MBTL1KMT2AKDM4EALDH1A1MEN1
SCHEMBL10286111 0.76 MAOB (0.33) MAOBMAOAKMT2APGK1POLB
SCHEMBL10286905 0.76 ALDH1A1 (0.33) KMT2AKDM4EALDH1A1GAAMEN1
SCHEMBL10286477 0.76 ALDH1A1 (0.48) KDM4EALDH1A1GLAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
WO-2012001040-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES MSR1, DDT, MPO L3MBTL1 850/4885MAOB 473/4885MAOA 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.