SCHEMBL10286305

SCHEMBL10286305

Cc1cc(-c2cc(Cl)cc(Cl)c2)c2c(n1)C(O)CCCC2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
UGT2B17 O75795 2/20 0.33
HTR1A P08908 1/20 0.32
HTR7 P34969 1/20 0.32
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10286098 0.96 ACHE (0.39) ACHEUGT2B17HTR1AHTR7
SCHEMBL10286341 0.88 ACHE (0.38) ACHEHTR1AHTR7
SCHEMBL10286055 0.84 HRH2 (0.41) ACHEUGT2B17HTTMEN1KMT2A
SCHEMBL10286067 0.84 ACHE (0.41) ACHEHTR1AHTR7
SCHEMBL10286349 0.83 ACHE (0.45) ACHEUGT2B17MEN1KMT2A
SCHEMBL10286382 0.81 CRHR1 (0.41) ACHE
SCHEMBL10286194 0.80 ACHE (0.40) ACHEUGT2B17HTT
SCHEMBL10286353 0.79 EPAS1 (0.35) ACHEUGT2B17
SCHEMBL526454 0.78 ACHE (0.49) ACHEUGT2B17MEN1KMT2A
SCHEMBL10286333 0.78 UGT2B17 (0.45) ACHEUGT2B17HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA CROP PROTECTION LLC (US) 2013-04-25 US disclosed
WO-2012001040-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2012-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130102631-A1 NOVEL MICROBIOCIDAL DIOXIME ETHER DERIVATIVES MSR1, DDT, MPO ACHE 660/4885UGT2B17 1446/4885HTR1A 2951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.